Prevention by calcium antagonists of profibrillatory effects of class I antiarrhythmic drugs in acute myocardial ischemia: study in pig heart in situ
B Bui‐Xuan, JF Aupetit, M Freysz… - … and Drug Therapy, 1997 - Wiley Online Library
… We assessed whether the calcium antagonist diltiazem (0.50 mg/kg bolus … prevent the
profibrillatory effect or even partially restore the antifibrillatory effect of a class I antiarrhythmic drug, …
profibrillatory effect or even partially restore the antifibrillatory effect of a class I antiarrhythmic drug, …
Class Ic antiarrhythmic drugs and myocardial ischaemia: study in the pig heart in situ
Q Timour, JF Aupetit, J Loufoua-Moundanga… - Naunyn-Schmiedeberg's …, 1991 - Springer
… enhance the prolongation of conduction time by 60% and do not prevent the 30% … manifested
profibrillatory properties (more pronounced than those of other class I antiarrhythmic drugs)…
profibrillatory properties (more pronounced than those of other class I antiarrhythmic drugs)…
Arrhythmogenicity of antiarrhythmic drugs and intraventricular conduction disorders: Possible aggravation by myocardial ischemia—Study in the porcine in situ heart
JF Aupetit, Q Timour, JP Larbre… - Cardiovascular drugs …, 1993 - Springer
… influence of other drugs, such as calcium channel blockers [10]… Effects of ischemia alone in
18 anesthetized, openchest pigs … antiarrhythmic action could then change into a profibrillatory …
18 anesthetized, openchest pigs … antiarrhythmic action could then change into a profibrillatory …
Calcium Antagonists and Prevention of Ventricular Fibrilla tion Induced by Transient or Persistent Ischemia
Q Timour, B Bui-Xuan, JF AUPETIT, M Freysz… - Japanese heart …, 1997 - jstage.jst.go.jp
… of this study was to compare in anesthetized, open-chest pigs, … in situ. Naunyn-Schmiedeberg's
Arch Pharmacol … of action of calcium antagonists in myocardial ischemia. Am J Cardiol …
Arch Pharmacol … of action of calcium antagonists in myocardial ischemia. Am J Cardiol …
Profibrillatory effects of lidocaine in the acutely ischemic porcine heart
JF Aupetit, Q Timour… - Journal of …, 1995 - journals.lww.com
… related to myocardial ischemia in the in situ heart of anesthetized open-chest pigs subjected
… widely used in the latest decades to prevent ventricular fibrillation (VF) in acute myocardial …
… widely used in the latest decades to prevent ventricular fibrillation (VF) in acute myocardial …
Attenuation of the ischaemia-induced fall of electrical ventricular fibrillation threshold by a calcium antagonist, diltiazem
JF Aupetit, Q Timour, G Chevrel… - Naunyn-Schmiedeberg's …, 1993 - Springer
… It was desirable that, in this study, myocardial ischaemia was not only … direction the
profibrillatory effect of antiarrhythmic drugs such as … Study in the porcine in situ heart. Cardiovasc …
profibrillatory effect of antiarrhythmic drugs such as … Study in the porcine in situ heart. Cardiovasc …
Ivabradine induces an increase in ventricular fibrillation threshold during acute myocardial ischemia: an experimental study
F Vaillant, Q Timour, J Descotes, W Manati… - Journal of …, 2008 - journals.lww.com
… of IVA on the threshold of ischemic VF in a pig model of brief … the profibrillatory or antifibrillatory
effects of a variety of drugs including … β-blockers and calcium antagonists increase VFT by …
effects of a variety of drugs including … β-blockers and calcium antagonists increase VFT by …
Role of ATP dependent potassium channels in myocardial ischaemia
GJ Gross, JA Auchampach - Cardiovascular research, 1992 - academic.oup.com
… in infarct size in intact in situ hearts. Thus the major goal of the … ischaemia and reperfusion
in isolated perfused guinea pig … profibrillatory effects, particularly in patients with a previous …
in isolated perfused guinea pig … profibrillatory effects, particularly in patients with a previous …
Trimetazidine demonstrated cardioprotective effects through mitochondrial pathway in a model of acute coronary ischemia
L Dehina, F Vaillant, A Tabib, B Bui-Xuan… - Naunyn-Schmiedeberg's …, 2013 - Springer
… , calcium channel antagonists prevent the profibrillatory effect or … The model used in this
study is a pig model of brief left … in preventing calcium overload during myocardial ischemia and …
study is a pig model of brief left … in preventing calcium overload during myocardial ischemia and …
Ischemia-induced action potential shortening is blunted by d-sotalol in a pig model of reversible myocardial ischemia
P Geelen, GE O'Hara, S Plante… - Journal of …, 2000 - journals.lww.com
… myocardial ischemia and class Ic antiarrhythmic drugs is now … class Ic drugs exhibit
profibrillatory effects in the presence of … and other antiarrhythmic drugs in preventing lethal …
profibrillatory effects in the presence of … and other antiarrhythmic drugs in preventing lethal …